ACS Stroke Sepsis

Cincinnati Stroke Program

tPA-Induced ICH

Management of Suspected ICH Following tPA

  1. Stop tPA Immediately
  2. Stat Noncontrast Head CT
  3. Vitals every 15 minutes
  4. Oxygen 2L NC, Maintain Sats >95%
  5. Labs: CBC, PT/PTT, Fibrinogen, T&C, 4 Units pRBCs, 4 Units FFP/Cryo
  6. Contact: Neurosurg, Family, PMD
  7. Strict BP Control (Nipride/Labetolol

If ICH Has Occurred:

  1. Obtain bleeding time
  2. Consult Hematologist
  3. If ele
  4. PT/INR-give FFP, if fibrinogen low-give cryoprecipitate 250(mg/unit)

References

Cincinnati Stroke Team, 2007. This pathway has not been prospectively validated.