ACS Stroke Sepsis

Early Goal-Directed Therapy (Sepsis) Program

Source ID and Control

1. ID a specific source (1C) and treated within the first 6 hours (1D).
2. Evaluate the pt for sources amenable to tissue debridement, drainage, removal of infected hardware/vascular access etc (1C).
3. The least invasive, yet most effective measure of source control should be employed (1D).
4. Intravascular access should be removed after other accesss is established (1C).
5. When peripancreatic necrosis is identified as a possible source, definitive therapy should be delayed until delineation between viable/nonviable tissue is made (2B).

Select Abbreviations Antibiotics APACHE II Bicarbonate Therapy Diagnosis DVT Prophylaxis Fluid Therapy Glucose Control Inotropic Support Levels Of Evidence Mechanical Ventilation of ALI/ARDS References Renal Replacement Sedation and Analgesia Sepsis Criteria Sepsis Definitions Source ID and Control Steroids Stress Ulcer Prophylaxis Vasopressors Xigris Indications

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