ACS Stroke Sepsis

Early Goal-Directed Therapy (Sepsis) Program

Sepsis Criteria

Criteria; Choose All That Apply
Temp >38 or <36C	Yes
HR >90 bpm	Yes
RR >20 or PaCO2 <32 mmHg	Yes
WBC >12K or <4K or Bands >10%	Yes
Source of Infection?	Yes
Organ Failure or Hypoperfusion? Organ dysfunction is defined as renal/liver/cardiac failure, acute lung injury, coagulation abnormalities, thrombocytopenia, CNS (AMS) or hypoperfusion with lactic acidosis. Hypoperfusion is septic shock, lactic acidosis or oliguria.	Yes
Sepsis-Induced Hypotension Refractory Hypotension is defined as a SBP <90mmHg, MAP <70mmHg or Systolic BP decrease of 40mmHg despite adequate fluide resuscitation (20-40 ml/kg fluid bolus)	Yes

References

Rivers E. et al, Early Goal Directed Therapy in the treatment of Severe Sepsis and Septic Shock. N Engl J Med, Vol 345, No. 19, Nov. 8, 2001.

Select Abbreviations Antibiotics APACHE II Bicarbonate Therapy Diagnosis DVT Prophylaxis Fluid Therapy Glucose Control Inotropic Support Levels Of Evidence Mechanical Ventilation of ALI/ARDS References Renal Replacement Sedation and Analgesia Sepsis Criteria Sepsis Definitions Source ID and Control Steroids Stress Ulcer Prophylaxis Vasopressors Xigris Indications

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